observed that rats fed with diets containing MCT consume less food compared with those fed with long chain triglycerides (LCT) containing food.
#Mct oil faqt cells trial#
Energy intake in normal-weight men at lunch was significantly lower after the MCT-containing breakfast than after all other breakfasts in a clinical trial of establishing the influence of chain length and satiety. A human study conducted in overweight men demonstrated that MCT consumption reduced food intake acutely in a glucagon-like peptide (GLP)-1, peptide YY (PYY) and insulin independent pathway.
Human and rodent studies have shown that MCT also play a role in food intake and satiety. Furthermore, addition of the combination of chilli and MCT to meals increased diet-induced thermogenesis by over 50% in heathy normal-weight humans. Rothwell and colleagues demonstrated that except for the elevated rates of energy expenditure, the reduction in weight gains of animals fed with MCT were possibly due to sympathetic activation of brown fat thermogenesis. Baba et al showed that MCT fed rats have less body weight, lower fat accumulation, smaller size of adipocytes and higher basal and stimulated metabolic rates. Studies in both human and rodents have shown that oxidation of MCFA that hydrolyzed from MCT induces weight loss through increasing energy expenditure and fat oxidation and helping in the process of excess calorie burning. Though inconsistence exists, a number of studies support the use of MCT as a supplement for weight loss. The effects of MCT in energy expenditure, food consumption, and fat deposition have been well investigated. Unlike long chain triglycerides (LCT), MCT will be broken down into glycerol and MCFAs, which will be directly absorbed into the blood stream and thereby transported to the target organs. MCT exists in natural foods with high percentage found in coconut oil, palm kernel oil, desiccated coconut, and raw coconut meat according to the US Department of Agriculture National Nutrient Database. MCT usually has 2 or 3 of the fatty acid chains belong to medium-chain fatty acids (MCFA).
Medium-chain triglycerides (MCT) is triglycerides composed of a glycerol backbone and three fatty acids that have an aliphatic tail of 6–12 carbon atoms.
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